@prefix this: <http://purl.org/np/RA0ZcmsH0t-s9CtgPX_y-ZBzYouG0TGOy5UXtzuDarQa0> .
@prefix sub: <http://purl.org/np/RA0ZcmsH0t-s9CtgPX_y-ZBzYouG0TGOy5UXtzuDarQa0#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix unii: <http://identifiers.org/unii/> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  umls:C1299487 a biolink:OrganismTaxon;
    rdfs:label "patients";
    biolink:category biolink:OrganismTaxon .
  
  unii:50VV3VW0TI a biolink:ChemicalEntity;
    rdfs:label "Atenolol";
    biolink:category biolink:ChemicalEntity .
  
  <http://purl.obolibrary.org/obo/MONDO_0004781> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "acute myocardial infarction";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0004981> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "atrial fibrillation";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0005010> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "coronary atherosclerosis";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0005044> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "hypertension";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/NCIT_C111100> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "supraventricular tachycardia";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  sub:_1 rdf:object <http://purl.obolibrary.org/obo/MONDO_0004781>;
    rdf:predicate biolink:treats;
    rdf:subject unii:50VV3VW0TI;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  sub:_2 rdf:object <http://www.ebi.ac.uk/efo/EFO_0003913>;
    rdf:predicate biolink:treats;
    rdf:subject unii:50VV3VW0TI;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  sub:_3 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005044>;
    rdf:predicate biolink:treats;
    rdf:subject unii:50VV3VW0TI;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  sub:_4 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005010>;
    rdf:predicate biolink:treats;
    rdf:subject unii:50VV3VW0TI;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  sub:_5 rdf:object <http://purl.obolibrary.org/obo/NCIT_C111100>;
    rdf:predicate biolink:treats;
    rdf:subject unii:50VV3VW0TI;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  sub:_6 rdf:object <http://purl.obolibrary.org/obo/MONDO_0004981>;
    rdf:predicate biolink:treats;
    rdf:subject unii:50VV3VW0TI;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  <http://www.ebi.ac.uk/efo/EFO_0003913> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "angina pectoris";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-10T16:19:07.394369"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627;
    prov:wasQuotedFrom "Atenolol is indicated for management of angina pectoris associated with coronary atherosclerosis. Management of acute myocardial infarction in hemodynamically stable patients with a heart rate greater than 50 beats per minutes and a systolic blood pressure above 100 mmHg. Management of atrial fibrillation and supraventricular tachycardia is indicated for hypertension alone and in combination with other antihypertensives." .
  
  biolink: pav:version "2.3.0" .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEApdULbl+/+pkVlq0fAzWmzfgIb+XMuQPKHMDVzUTWCZBjLfzORll42ptr52e4w7tTYkUKrBsQbx8lkjZWAlWiyh+xIK0oLFSdYRSt63kgiyRYBUOR+spcgmofb7f6JyftArPVTKhsWOMt/mcyNG9qc3lw8B/xuPmLteUWO33xWhfXQreTw1lsGUkZ1j4cB4X9HIuI20ktLYLCXaBauNHEJZ4qp6/Q2ATsJcw8tg7aRmFKXhrjM9maZ2+0cMg0Jpmn2UnDlPKXEA6Qq+qnvvQt8KFjIzP9FTMyvrWl8tTd0NCmS9VpooZJQ8We1lGMPXg5bMbe/bVkTf70fbFMf0RKrQIDAQAB";
    npx:hasSignature "G1NMzgAQGRluWbmAI1zrpUcZ7R96GYK0Tj5cwpfHrvPl4rjbd7BlPBvxaLIGIC1niTBtcKS0o9A/K5pfHdJhbVaReiWAF2C5KbXvbcYy0KrASgR6Hp+0q4fKUlIsgfXXxMUtNkNkMCAUeOGGnbk2uGAZDrUu6dTCr1tmE6jYCAcFofW95R7qbLYrfaGskbyA8ogZwtKlVr3fp63XbWSQAVrOSyWO5yhmjtOGX5E5Dul36a+Tdk44cPW49hA/K4X5JchSsoQUbLSDUJAGna0XR3u7GPC0sj+5aGwCzadq3PyJqOO1PaVtOyQCD2d1EY7KP3cgb1HqYvEgEAfwjUjgew==";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2022-10-10T16:19:07.394369"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 .
}