@prefix this: <http://purl.org/np/RAHJOTpJkx8P2nITumzJm5VRljOh44hZbN8k-nLObyZAw> .
@prefix sub: <http://purl.org/np/RAHJOTpJkx8P2nITumzJm5VRljOh44hZbN8k-nLObyZAw#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://identifiers.org/pubchem.compound/392622> a biolink:ChemicalEntity;
    rdfs:label "ritonavir";
    biolink:category biolink:ChemicalEntity .
  
  <http://identifiers.org/pubchem.compound/441243> a biolink:ChemicalEntity;
    rdfs:label "Invirase";
    biolink:category biolink:ChemicalEntity .
  
  <http://purl.obolibrary.org/obo/MONDO_0004951> a biolink:OrganismTaxon;
    rdfs:label "HIV-1";
    biolink:category biolink:OrganismTaxon .
  
  <http://purl.obolibrary.org/obo/MONDO_0005109> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "HIV infection";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  sub:_1 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005109>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/441243>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ae7c54b1-b440-4cca-97e8-e5b825413d32> .
  
  sub:_2 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005109>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/392622>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ae7c54b1-b440-4cca-97e8-e5b825413d32> .
  
  sub:_3 rdf:object <http://identifiers.org/pubchem.compound/392622>;
    rdf:predicate biolink:interacts_with;
    rdf:subject <http://identifiers.org/pubchem.compound/441243>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ae7c54b1-b440-4cca-97e8-e5b825413d32> .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-13T12:29:39.252703"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627;
    prov:wasQuotedFrom " Invirase in combination with ritonavir and other antiretroviral agents is indicated for the treatment of HIV-1 infection in adults (over the age of 16 years) in adults. InvirASE is indicated to be an effective form of treatment for adults over the ages of 16. In addition to other anti-HIV-1 agents, INVIRASE is also indicated for adults with age 16-years-old HIV infection." .
  
  biolink: pav:version "2.3.0" .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEApdULbl+/+pkVlq0fAzWmzfgIb+XMuQPKHMDVzUTWCZBjLfzORll42ptr52e4w7tTYkUKrBsQbx8lkjZWAlWiyh+xIK0oLFSdYRSt63kgiyRYBUOR+spcgmofb7f6JyftArPVTKhsWOMt/mcyNG9qc3lw8B/xuPmLteUWO33xWhfXQreTw1lsGUkZ1j4cB4X9HIuI20ktLYLCXaBauNHEJZ4qp6/Q2ATsJcw8tg7aRmFKXhrjM9maZ2+0cMg0Jpmn2UnDlPKXEA6Qq+qnvvQt8KFjIzP9FTMyvrWl8tTd0NCmS9VpooZJQ8We1lGMPXg5bMbe/bVkTf70fbFMf0RKrQIDAQAB";
    npx:hasSignature "DHTooBXtRW6tovGdPB6jCcjqJ6M63/p7d08xpYmHmCsGbHzzFKlHOKxMY0lLw0ZHoQXM7rrXZgpRDqt1XM/IG2toaEG7ZgEnBhN/k0uW5ScRiJ7VfJCd/0yv3hUEl7N+XWTMHlybNo8qMwhI8NsWz6K/ZHShqaoGgwgxhTD0Zh7RF1lZAPnCvG3ViIJ7qtibbU7jQf9XTdUMW6TTQkyczEFgvLEugh7JcDU2QhIEvXV/cGeQZ9K1ATH32ADSfNtRBlFAjuo2kFXD99p3dIfvP5zKXnQy4VnkFspx3yEP8B9HR/pbgQfWPov4me8d+ZDPFUoxEXxFdwbnHUsQ4usRZw==";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2022-10-13T12:29:39.252703"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 .
}