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[However, biological and evolutionary insights into the structure and principle function of the kidney and the blood pressure sustaining machinery, with the extracellular fluid volume and the renin-angiotensin system acting as a central player, clearly indicate that salt has been a precious commodity in the terrestrial animal kingdom and that essential hypertension may be a consequence of the kidney's maladaptation to excess salt intake, which is specific to recent human civilization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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