. . . . . . . "[However, a region on chromosome 4p16, adjacent to the MSX1 and STX18 genes, was associated (P = 9.5 � 10??) with the risk of ostium secundum atrial septal defect (ASD) in the discovery cohort (N = 340 cases), and this association was replicated in a further 417 ASD cases and 2,520 controls (replication P = 5.0 � 10??; odds ratio (OR) in replication cohort = 1.40, 95% confidence interval (CI) = 1.19-1.65; combined P = 2.6 � 10?�?).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:14:44+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .