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@prefix sub: <http://purl.org/np/RAij_2PjTIiRg7W6HuNv7IA3a7E45Irag85VtA3RHJhuY#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubInfo ;
    a np:Nanopublication .
}
sub:assertion {
  <http://identifiers.org/pubchem.compound/1993> a biolink:ChemicalEntity ;
    rdfs:label "methacholine" ;
    biolink:category biolink:ChemicalEntity .
  umls:C0004096 a biolink:DiseaseOrPhenotypicFeature ;
    rdfs:label "asthma" ;
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  <http://purl.obolibrary.org/obo/MONDO_0006731> a biolink:DiseaseOrPhenotypicFeature ;
    rdfs:label "hyperactivity" ;
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  sub:_1 rdf:predicate biolink:associated_with ;
    rdf:subject <http://identifiers.org/pubchem.compound/1993> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
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  sub:_2 rdf:object umls:C0004096 ;
    rdf:predicate biolink:treats ;
    rdf:subject <file:///app/Provocholine> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1967dc24-f2a5-4095-baa9-a9d1c5410311> .
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    rdf:predicate biolink:treats ;
    rdf:subject <file:///app/Provocholine> ;
    a biolink:Association ;
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    biolink:category biolink:Association ;
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  sub:_5 rdf:predicate biolink:treats ;
    rdf:subject <file:///app/Provocholine> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1967dc24-f2a5-4095-baa9-a9d1c5410311> .
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  sub:_7 rdf:object <http://purl.obolibrary.org/obo/MONDO_0006731> ;
    rdf:predicate biolink:treats ;
    rdf:subject <file:///app/Provocholine> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1967dc24-f2a5-4095-baa9-a9d1c5410311> .
  sub:_8 rdf:object <http://identifiers.org/pubchem.compound/1993> ;
    rdf:predicate biolink:active_in ;
    rdf:subject <file:///app/Provocholine> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1967dc24-f2a5-4095-baa9-a9d1c5410311> .
  sub:_9 rdf:object umls:C0004096 ;
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}
sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-10T14:48:14.289125"^^xsd:dateTime ;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 ;
    prov:wasQuotedFrom " Provocholine, used in methacholine challenge test, is indicated for the diagnosis of bronchial airway hyperreactivity in adults and pediatric patients five years of age and older who do not have clinically apparent asthma. The drug is used in the challenge test to diagnose bronchia airwayhyperreactivity and hyperactivity in children and adults aged five to seven years old with no apparent signs of asthma." .
  biolink: pav:version "2.3.0" .
}
sub:pubInfo {
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}