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@prefix sub: <http://purl.org/np/RAxUNp6Zzewjij_yJWv_hg8iqTFiOC2r4HnHBiL6lgjYo#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubInfo ;
    a np:Nanopublication .
}
sub:assertion {
  mesh:C034260 a biolink:GeneOrGeneProduct ;
    rdfs:label "protease" ;
    biolink:category biolink:GeneOrGeneProduct .
  <http://identifiers.org/pubchem.compound/131536> a biolink:ChemicalEntity ;
    rdfs:label "Fosamprenavir" ;
    biolink:category biolink:ChemicalEntity .
  <http://identifiers.org/pubchem.compound/392622> a biolink:ChemicalEntity ;
    rdfs:label "ritonavir" ;
    biolink:category biolink:ChemicalEntity .
  <http://identifiers.org/pubchem.compound/5460341> a biolink:ChemicalEntity ;
    rdfs:label "calcium" ;
    biolink:category biolink:ChemicalEntity .
  umls:C1299487 a biolink:OrganismTaxon ;
    rdfs:label "patients" ;
    biolink:category biolink:OrganismTaxon .
  umls:C1306577 a biolink:OrganismTaxon ;
    rdfs:label "patient" ;
    biolink:category biolink:OrganismTaxon .
  <http://purl.obolibrary.org/obo/CHEBI_37670> a biolink:GeneOrGeneProduct ;
    rdfs:label "protease. inhibitor" ;
    biolink:category biolink:GeneOrGeneProduct .
  sub:_1 rdf:predicate biolink:treats ;
    rdf:subject <http://identifiers.org/pubchem.compound/131536> ;
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    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
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    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1967dc24-f2a5-4095-baa9-a9d1c5410311> .
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sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-10T14:43:24.030767"^^xsd:dateTime ;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 ;
    prov:wasQuotedFrom "Fosamprenavir calcium tablets are indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus (HIV-1) infection. The protease inhibitor-experienced patient trial was not large enough to reach a definitive conclusion. Once-daily administration of fosampranavir. tabletsplus ritonavir is not recommended for adult. protease. inhibitor-expertienced patients or any pediatric patients. younger than 6 months." .
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